SINGLE-CELL HETEROGENEITY AND DYNAMIC EVOLUTION OF PH-LIKE ACUTE LYMPHOBLASTIC LEUKEMIA PATIENT WITH NOVEL TPR-PDGFRB FUSION GENE

Single-cell heterogeneity and dynamic evolution of Ph-like acute lymphoblastic leukemia patient with novel TPR-PDGFRB fusion gene

Abstract Philadelphia chromosome-like acute lymphoblastic leukemia (Ph-like ALL) is a refractory and recurrent subtype of B-cell ALL enriched with kinase-activating rearrangements.Incomplete understanding of the heterogeneity within the tumor cells presents a major challenge for the Charging Stand diagnosis and therapy of Ph-like ALL.Here, we exhib

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Congenital cervical rib causing thoracic outlet syndrome

Background: Thoracic Outlet Syndrome (TOS) is a common condition caused by compression of Induction Hobs neurovascular vessels traveling through the thoracic outlet.There are three categories of TOS, arterial (aTOS), neurogenic (nTOS), and venous (vTOS).These commonly present with pain in the neck, upper extremity weakness, paresthesia, swelling, a

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